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Flights from Santa Ana John Wayne Airport to Iowa

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Flight deals from Santa Ana John Wayne Airport to Iowa

Looking for cheap tickets from Santa Ana John Wayne Airport to Iowa, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.
Des Moines.£80 per passenger.Departing Thu, 11 Sep, returning Sun, 14 Sep.Return flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Santa Ana John Wayne on Thu, 11 Sep, arriving in Des Moines.Inbound direct flight with Allegiant Air departs from Des Moines on Sun, 14 Sep, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £80, select.
Cedar Rapids.£249 per passenger.Departing Thu, 19 Jun, returning Mon, 23 Jun.Return flight with Spirit Airlines and Allegiant Air.Outbound indirect flight with Spirit Airlines, departs from Santa Ana John Wayne on Thu, 19 Jun, arriving in Cedar Rapids.Inbound indirect flight with Allegiant Air, departs from Cedar Rapids on Mon, 23 Jun, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £249, select.
Sioux City.£496 per passenger.Departing Fri, 4 Jul, returning Sun, 6 Jul.Return flight with United.Outbound indirect flight with United, departs from Santa Ana John Wayne on Fri, 4 Jul, arriving in Sioux City.Inbound indirect flight with United, departs from Sioux City on Sun, 6 Jul, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £496, select.
Mason City.£621 per passenger.Departing Wed, 18 Jun, returning Sun, 22 Jun.Return flight with United.Outbound indirect flight with United, departs from Santa Ana John Wayne on Wed, 18 Jun, arriving in Mason City.Inbound indirect flight with United, departs from Mason City on Sun, 22 Jun, arriving in Santa Ana John Wayne.Price includes taxes and charges.From £621, select.

Flying from Santa Ana John Wayne Airport to Iowa

Arm yourself with these facts on the fly.
Cheapest flight found£80, Des Moines
Cheapest month to flySeptember
Average flight time3 hrs, 19 mins
Average flights per week6
Most popular airlineAllegiant Air

Frequently asked questions

Yes - direct flights currently operate from Santa Ana John Wayne Airport to Des Moines Airport in Iowa.
We looked at all of the upcoming return flights from Santa Ana John Wayne Airport to Iowa we could find over the next 12 months. It looks like £80 is the best price. This is good, compared to the average Iowa ticket price of £203.
The cheapest month to fly from Santa Ana John Wayne Airport to Sioux City Airport is currently July.
The cheapest month to fly from Santa Ana John Wayne Airport to Cedar Rapids Airport is currently June.
The cheapest month to fly from Santa Ana John Wayne Airport to Mason City Airport is currently June.
And the cheapest month to fly from Santa Ana John Wayne Airport to Des Moines Airport is usually September.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Santa Ana John Wayne Airport to Iowa on Thursday, 11 September 2025.
If you're flying from Santa Ana John Wayne, the cheapest city in Iowa to fly into is Des Moines. The cheapest airport serving Des Moines at the moment is Des Moines.
The average flight time between Santa Ana John Wayne Airport and Iowa is 3 hours and 19 minutes.