Cheap Flights from Chicago to Cuzco Region from £375 Return

Flight deals from Chicago to Cuzco Region

Looking for cheap tickets from Chicago to Cuzco Region, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Cuzco.£375 per passenger.Departing Mon, 12 Jan, returning Mon, 19 Jan.Return flight with Spirit Airlines and LATAM Airlines.Outbound indirect flight with Spirit Airlines, departs from Chicago O'Hare International on Mon, 12 Jan, arriving in Cuzco.Inbound indirect flight with LATAM Airlines, departs from Cuzco on Mon, 19 Jan, arriving in Chicago O'Hare International.Price includes taxes and charges.From £375, select.

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Flying from Chicago to Cuzco Region

Arm yourself with these facts on the fly.

Cheapest flight found	£375
Cheapest month to fly	January
Cheapest airport to fly from	Chicago O'Hare International

How to find cheap flights from Chicago to Cuzco Region

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from Chicago to Cuzco Region. Other savvy travellers recently found return flights from £375 and one-way tickets from £188 one-way. Ready to join them? Here are a few tips to help you do it the smart way.

Fly from Chicago O'Hare International into Cuzco

At the moment, the lowest priced flight tickets to Cuzco Region are from Chicago O'Hare International Airport to Cuzco Airport.

Fly in January

We crunched the flight calendar and found the cheapest time to fly from Chicago to Cuzco Region is currently January.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Chicago to anywhere you choose in Cuzco Region.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from Chicago to Cuzco Region go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the Cuzco Region to Cuzco Region flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

What's the average Chicago to Cuzco Region flight price?

We looked at all of the upcoming return flights from Chicago to Cuzco Region we could find over the next 12 months. It looks like £375 is the best price. This is good, compared to the average Cuzco Region ticket price of £375.

What is the cheapest month to fly from Chicago to Cuzco Region?

The cheapest month to fly from Chicago to Cuzco Region is currently January.

Which upcoming date is cheapest to fly from Chicago to Cuzco Region on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Chicago to Cuzco Region on Monday, 12 January 2026.