Flights from Rome to Santiago Metropolitan Region

Travellers and cabin class

Flight deals from Rome to Santiago Metropolitan Region

Looking for cheap tickets from Rome to Santiago Metropolitan Region, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Flying from Rome to Santiago Metropolitan Region

Arm yourself with these facts on the fly.
Cheapest flight found£569, Santiago
Cheapest month to flyJanuary
Cheapest airport to fly fromRome Fiumicino

Frequently asked questions

We looked at all of the upcoming return flights from Rome to Santiago Metropolitan Region we could find over the next 12 months. It looks like £569 is the best price. This is good, compared to the average Santiago Metropolitan Region ticket price of £759.
The cheapest month to fly from Rome to Santiago Metropolitan Region is currently January.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Rome to Santiago Metropolitan Region on Saturday, 24 January 2026.
Currently, there aren't any direct flights from Rome to Santiago Metropolitan Region, but you can still fly with a stopover.
If you're flying from Rome, the cheapest city in Santiago Metropolitan Region to fly into is Santiago. The cheapest airport serving Santiago at the moment is Santiago Arturo Merino Benitez.