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Flights from Louisville Muhammad Ali International Airport to South Carolina

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Flight deals from Louisville Muhammad Ali International Airport to South Carolina

Looking for cheap tickets from Louisville Muhammad Ali International Airport to South Carolina, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.
Myrtle Beach.£58 per passenger.Departing Sat, 2 Aug, returning Sat, 9 Aug.Return flight with Allegiant Air.Outbound direct flight with Allegiant Air departs from Louisville Muhammad Ali International on Sat, 2 Aug, arriving in Myrtle Beach International .Inbound direct flight with Allegiant Air departs from Myrtle Beach International on Sat, 9 Aug, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From £58, select.
Charleston.£65 per passenger.Departing Fri, 12 Sep, returning Fri, 19 Sep.Return flight with Breeze Airways.Outbound direct flight with Breeze Airways departs from Louisville Muhammad Ali International on Fri, 12 Sep, arriving in Charleston.Inbound direct flight with Breeze Airways departs from Charleston on Fri, 19 Sep, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From £65, select.
Columbia.£176 per passenger.Departing Tue, 24 Jun, returning Sat, 28 Jun.Return flight with Delta.Outbound indirect flight with Delta, departs from Louisville Muhammad Ali International on Tue, 24 Jun, arriving in Columbia Metropolitan.Inbound indirect flight with Delta, departs from Columbia Metropolitan on Sat, 28 Jun, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From £176, select.
Greenville.£284 per passenger.Departing Fri, 20 Jun, returning Tue, 24 Jun.Return flight with Delta.Outbound indirect flight with Delta, departs from Louisville Muhammad Ali International on Fri, 20 Jun, arriving in Greenville-Spartanburg.Inbound indirect flight with Delta, departs from Greenville-Spartanburg on Tue, 24 Jun, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From £284, select.

Flying from Louisville Muhammad Ali International Airport to South Carolina

Arm yourself with these facts on the fly.
Cheapest flight found£58, Myrtle Beach
Cheapest month to flyAugust
Average flight time1 hr, 32 mins
Average flights per week6
Most popular airlineSpirit Airlines

Frequently asked questions

Yes - direct flights currently operate from Louisville Muhammad Ali International Airport to Myrtle Beach International Airport and Charleston Airport in South Carolina.
We looked at all of the upcoming return flights from Louisville Muhammad Ali International Airport to South Carolina we could find over the next 12 months. It looks like £58 is the best price. This is good, compared to the average South Carolina ticket price of £122.
The cheapest month to fly from Louisville Muhammad Ali International Airport to Myrtle Beach International Airport is currently August.
The cheapest month to fly from Louisville Muhammad Ali International Airport to Columbia Metropolitan Airport is currently June.
The cheapest month to fly from Louisville Muhammad Ali International Airport to Greenville-Spartanburg Airport is currently June.
And the cheapest month to fly from Louisville Muhammad Ali International Airport to Charleston Airport is usually September.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Louisville Muhammad Ali International Airport to South Carolina on Saturday, 2 August 2025.
If you're flying from Louisville Muhammad Ali International, the cheapest city in South Carolina to fly into is Myrtle Beach. The cheapest airport serving Myrtle Beach at the moment is Myrtle Beach International .
The average flight time between Louisville Muhammad Ali International Airport and South Carolina is 1 hour and 32 minutes.