Skyscanner home

Flights from San Francisco International Airport to South Carolina

Flight deals from San Francisco International Airport to South Carolina

Looking for a cheap last-minute deal or the best roundtrip flight from San Francisco International Airport to South Carolina? If you want to travel next month, roundtrip fares start from £260. Find the lowest prices on one-way and roundtrip tickets right here.
Charleston.£191 per passenger.Departing Sat, Sep 5, returning Wed, Sep 9.Round-trip flight with Breeze Airways.Outbound indirect flight with Breeze Airways, departing from San Francisco International on Sat, Sep 5, arriving in Charleston.Inbound indirect flight with Breeze Airways, departing from Charleston on Wed, Sep 9, arriving in San Francisco International.Price includes taxes and charges.From £191, select.
Columbia.£266 per passenger.Departing Fri, Oct 23, returning Mon, Oct 26.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from San Francisco International on Fri, Oct 23, arriving in Columbia Metropolitan.Inbound indirect flight with Delta, departing from Columbia Metropolitan on Mon, Oct 26, arriving in San Francisco International.Price includes taxes and charges.From £266, select.
Greenville.£285 per passenger.Departing Wed, Aug 12, returning Wed, Aug 19.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from San Francisco International on Wed, Aug 12, arriving in Greenville-Spartanburg.Inbound indirect flight with Delta, departing from Greenville-Spartanburg on Wed, Aug 19, arriving in San Francisco International.Price includes taxes and charges.From £285, select.
Myrtle Beach.£301 per passenger.Departing Tue, Jul 28, returning Tue, Aug 4.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from San Francisco International on Tue, Jul 28, arriving in Myrtle Beach International.Inbound indirect flight with Delta, departing from Myrtle Beach International on Tue, Aug 4, arriving in San Francisco International.Price includes taxes and charges.From £301, select.
Hilton Head Island.£305 per passenger.Departing Wed, Jun 24, returning Tue, Jun 30.Round-trip flight with United.Outbound indirect flight with United, departing from San Francisco International on Wed, Jun 24, arriving in Hilton Head.Inbound indirect flight with United, departing from Hilton Head on Tue, Jun 30, arriving in San Francisco International.Price includes taxes and charges.From £305, select.
Show more deals

Flying from San Francisco International Airport to South Carolina

Arm yourself with these facts on the fly.
Cheapest flight found£191
Cheapest month to flySeptember

Frequently asked questions

There are currently no direct flights from San Francisco International Airport to South Carolina, but we've found some other routes to United States – check them out now.
We looked at all of the upcoming round-trip flights from San Francisco International Airport to South Carolina we could find over the next 12 months. It looks like £191 is the best price. This is good, compared to the average South Carolina ticket price of £269.
The cheapest month to fly from San Francisco International Airport to Charleston Airport is currently September.
The cheapest month to fly from San Francisco International Airport to Greenville-Spartanburg Airport is currently August.
The cheapest month to fly from San Francisco International Airport to Hilton Head Airport is currently June.
And the cheapest month to fly from San Francisco International Airport to Columbia Metropolitan Airport is usually October.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from San Francisco International Airport to South Carolina on Saturday, September 5, 2026.
If you're flying from San Francisco International, the cheapest city in South Carolina to fly into is Charleston. The cheapest airport serving Charleston at the moment is Charleston.

More travel options