Cheap Flights from Myrtle Beach to Sicily from £726 Return

Flight deals from Myrtle Beach to Sicily

Looking for cheap tickets from Myrtle Beach to Sicily, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Palermo.£726 per passenger.Departing Sun, 5 Apr, returning Sun, 12 Apr.Return flight with Spirit Airlines and Ryanair.Outbound indirect flight with Spirit Airlines, departs from Myrtle Beach International on Sun, 5 Apr, arriving in Palermo.Inbound indirect flight with Ryanair, departs from Palermo on Sun, 12 Apr, arriving in Myrtle Beach International .Price includes taxes and charges.From £726, select.

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Flying from Myrtle Beach to Sicily

Arm yourself with these facts on the fly.

Cheapest flight found	£726
Cheapest month to fly	April
Cheapest airport to fly from	Myrtle Beach International

How to find cheap flights from Myrtle Beach to Sicily

Ready to join the other savvy travellers booking the cheapest one-way and return flights to Sicily? Here are a few tips to help you do it the smart way.

Fly from Myrtle Beach International into Palermo

At the moment, the lowest priced flight tickets to Sicily are from Myrtle Beach International Airport to Palermo Airport.

Fly in April

We crunched the flight calendar and found the cheapest time to fly from Myrtle Beach to Sicily is currently April.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Myrtle Beach to anywhere you choose in Sicily.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from Myrtle Beach to Sicily go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the Sicily to Sicily flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

What's the average Myrtle Beach to Sicily flight price?

We looked at all of the upcoming return flights from Myrtle Beach to Sicily we could find over the next 12 months. It looks like £726 is the best price. This is good, compared to the average Sicily ticket price of £726.

What is the cheapest month to fly from Myrtle Beach to Sicily?

The cheapest month to fly from Myrtle Beach to Sicily is currently April.

Which upcoming date is cheapest to fly from Myrtle Beach to Sicily on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Myrtle Beach to Sicily on Sunday, 5 April 2026.

Are there any direct flights from Myrtle Beach to Sicily?

Currently, there aren't any direct flights from Myrtle Beach to Sicily, but you can still fly with a stopover.

If I'm flying from Myrtle Beach, where in Sicily is cheapest to fly into?

If you're flying from Myrtle Beach, the cheapest city in Sicily to fly into is Palermo. The cheapest airport serving Palermo at the moment is Palermo.